OVEREXPRESSION OF MIR-99A PROMOTED EXPANSION AND SUPPRESSED DIFFERENTIATION OF HEMATOPOIETIC STEM/PROGENITOR CELLS

Overexpression of miR-99a promoted expansion and suppressed differentiation of hematopoietic stem/progenitor cells

Abstract MicroRNAs (miRNAs) are a class of non-coding RNAs involved in a variety of pathophysiological processes.We have previously reported that the abnormally high expression of miR-99a is associated with drug resistance and poor prognosis in acute myeloid leukemia.However, the impact of miR-99a on normal hematopoiesis is not well understood.To i

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Differential T cell response against BK virus regulatory and structural antigens: A viral dynamics modelling approach.

BK virus (BKV) associated nephropathy affects 1-10% of kidney transplant recipients, leading to graft failure in about 50% of cases.Immune responses against different BKV antigens have been shown to have a prognostic value for disease development.Data currently suggest that the structural antigens and regulatory antigens of BKV might each trigger a

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DESAIN MODEL PERAMALAN JUMLAH KERUSAKAN SIM CARD

Informasi memiliki arti yang sangat penting dalam era globalisasi seperti saat ini.Kesuksesan seseorang bahkan ditentukan dari kemampuannya mengakses dan mengolah informasi.Alat untuk mengakses informasipun dibuat sesimple dan sepraktis mungkin.Para penyedia layanan provider bersaing untuk memberikan layanan terbaik dalam bidang pengaksesan informa

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